Rudi D'Hooge Selected Research

Mannosidase Deficiency Diseases (Mannosidosis)

1/2011	Cerebellar alterations and gait defects as therapeutic outcome measures for enzyme replacement therapy in α-mannosidosis.
8/2006	Multivariate neurocognitive and emotional profile of a mannosidosis murine model for therapy assessment.

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Rudi D'Hooge Research Topics

Disease

22	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 09/2005
8	Lysosomal Storage Diseases (Lysosomal Storage Disease) 11/2015 - 05/2003
7	Cognitive Dysfunction 01/2020 - 01/2003
7	Metachromatic Leukodystrophy (Sulfatide Lipidosis) 07/2015 - 09/2007
6	Amyloid Plaque 01/2018 - 01/2008
6	Intellectual Disability (Idiocy) 01/2017 - 02/2006
6	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2015 - 10/2008
5	alpha-Mannosidosis 10/2017 - 07/2005
4	Leukemia 01/2021 - 01/2017
4	Neuralgia (Stump Neuralgia) 11/2012 - 11/2006
3	Tauopathies 01/2020 - 11/2011
3	Neuroinflammatory Diseases 01/2018 - 01/2015
3	Gliosis 01/2018 - 04/2008
3	Seizures (Absence Seizure) 09/2015 - 07/2003
3	Parkinson Disease (Parkinson's Disease) 03/2015 - 11/2013
3	Pain (Aches) 11/2012 - 07/2008
2	Autism Spectrum Disorder 01/2021 - 03/2013
2	Schizophrenia (Dementia Praecox) 01/2019 - 07/2011
2	Fucosidosis 01/2018 - 01/2016
2	Nervous System Diseases (Neurological Disorders) 11/2015 - 04/2009
2	Fragile X Syndrome (Martin Bell Syndrome) 07/2015 - 02/2013
2	Demyelinating Diseases (Demyelinating Disease) 07/2015 - 06/2012
2	Memory Disorders (Memory Loss) 12/2013 - 06/2012
2	Hypersensitivity (Allergy) 05/2013 - 03/2010
2	Mucopolysaccharidoses 06/2012 - 05/2003
2	Mannosidase Deficiency Diseases (Mannosidosis) 01/2011 - 08/2006
2	Ataxia (Dyssynergia) 02/2009 - 11/2008
1	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 10/2020
1	Congenital Abnormalities (Deformity) 01/2020
1	Amnesia (Dissociative Amnesia) 10/2019
1	Autistic Disorder (Autism) 01/2019
1	Clinical Deterioration 01/2018
1	Female-Restricted Epilepsy with Mental Retardation 01/2017
1	Leukoencephalopathies 01/2017
1	Brain Diseases (Brain Disorder) 11/2016
1	Muscular Diseases (Myopathy) 01/2015
1	Type A Niemann-Pick Disease 01/2015

Drug/Important Bio-Agent (IBA)

18	Amyloid (Amyloid Fibrils)IBA 01/2020 - 01/2003
13	Proteins (Proteins, Gene)FDA Link 01/2021 - 02/2006
7	Peptides (Polypeptides)IBA 01/2019 - 01/2008
6	Cerebroside-Sulfatase (Arylsulfatase A)IBA 07/2015 - 09/2007
5	alpha-Mannosidase (LAMAN)IBA 10/2017 - 07/2005
5	EnzymesIBA 11/2015 - 05/2003
3	Pharmaceutical PreparationsIBA 01/2019 - 05/2013
3	Lysergic Acid Diethylamide (LSD)IBA 01/2018 - 04/2009
3	AcidsIBA 10/2017 - 01/2015
3	HydrolasesIBA 01/2016 - 04/2009
3	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 10/2015 - 09/2005
3	ursodoxicoltaurineIBA 01/2015 - 06/2012
2	Folic Acid (Vitamin M)FDA LinkGeneric 01/2020 - 01/2019
2	tau Proteins (tau Protein)IBA 01/2020 - 02/2013
2	Methotrexate (Mexate)FDA LinkGeneric 01/2019 - 01/2018
2	Amyloid beta-PeptidesIBA 01/2016 - 09/2005
2	OligosaccharidesIBA 11/2015 - 01/2011
2	RNA (Ribonucleic Acid)IBA 07/2015 - 03/2013
2	alpha-SynucleinIBA 03/2015 - 11/2013
2	Protein Isoforms (Isoforms)IBA 01/2015 - 11/2011
2	GlycosaminoglycansIBA 06/2012 - 05/2003
2	Sulfoglycosphingolipids (Sulfatides)IBA 07/2011 - 09/2007
2	LipidsIBA 04/2008 - 01/2008
1	Methylenetetrahydrofolate Reductase (NADPH2) (Methylenetetrahydrofolate Reductase)IBA 01/2021
1	ProgranulinsIBA 10/2020
1	Lysosomal Membrane ProteinsIBA 10/2020
1	Protein Phosphatase 2 (Protein Phosphatase 2A)IBA 01/2020
1	Selenic AcidIBA 01/2020
1	Scopolamine (Hyoscine)FDA Link 10/2019
1	Muscarinic AntagonistsIBA 10/2019
1	MicroRNAs (MicroRNA)IBA 10/2018
1	SeleniumIBA 01/2018
1	PresenilinsIBA 01/2018
1	Biomarkers (Surrogate Marker)IBA 01/2018
1	NestinIBA 01/2018
1	AntioxidantsIBA 01/2018
1	N-Acetylneuraminic Acid (Sialic Acid)IBA 01/2017
1	CorticosteroneIBA 01/2017
1	Dopamine (Intropin)FDA LinkGeneric 01/2017
1	TetraspaninsIBA 01/2017
1	Tryptophan (L-Tryptophan)FDA Link 11/2016
1	Quinolinic AcidIBA 11/2016
1	alpha-L-Fucosidase (Fucosidase)IBA 01/2016
1	GlycoconjugatesIBA 01/2016
1	Mannose (D-Mannose)IBA 11/2015
1	Heterotrimeric GTP-Binding Proteins (Heterotrimeric G-Proteins)IBA 10/2015
1	Carrier Proteins (Binding Protein)IBA 10/2015
1	Guanine NucleotidesIBA 10/2015
1	Phosphotransferases (Kinase)IBA 09/2015
1	Fragile X Mental Retardation ProteinIBA 07/2015
1	Monocyte Chemoattractant ProteinsIBA 07/2015
1	ChemokinesIBA 07/2015
1	Simvastatin (Zocor)FDA LinkGeneric 07/2015
1	InterleukinsIBA 07/2015
1	Macrophage Inflammatory Proteins (Macrophage Inflammatory Protein 1)IBA 07/2015
1	CytokinesIBA 07/2015
1	GlycogenIBA 01/2015
1	Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA 01/2015
1	SphingomyelinsIBA 01/2015

Therapy/Procedure

5	Therapeutics 01/2018 - 08/2006
5	Enzyme Replacement Therapy 10/2017 - 11/2008
2	Drug Therapy (Chemotherapy) 01/2021 - 01/2017
2	Intravenous Injections 06/2012 - 09/2007